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Page 1
Initial productive and latent HIV infections originate in vivo by infection of resting T cells.
Wietgrefe SW, Anderson J, Duan L, Southern PJ, Zuck P, Wu G, Howell BJ, Reilly C, Kroon E, Chottanapund S, Buranapraditkun S, Sacdalan C, Tulmethakaan N, Colby DJ, Chomchey N, Prueksakaew P, Pinyakorn S, Trichavaroj R, Mitchell JL, Trautmann L, Hsu D, Vasan S, Manasnayakorn S, de Souza M, Tovanabutra S, Schuetz A, Robb ML, Phanuphak N, Ananworanich J, Schacker TW, Haase AT; RV254/SEARCH 010 Study Team. Wietgrefe SW, et al. Among authors: chomchey n. J Clin Invest. 2023 Nov 15;133(22):e171501. doi: 10.1172/JCI171501. J Clin Invest. 2023. PMID: 37733443 Free PMC article.
Phase II prefusion non-stabilised Covid-19 mRNA vaccine randomised study.
Puthanakit T, Prompetchara E, Gatechompol S, Ketloy C, Thitithanyanont A, Jongkaewwattana A, Buranapraditkun S, Ubolyam S, Kerr SJ, Sophonphan J, Apornpong T, Kittanamongkolchai W, Siwamogsatham S, Sriplienchan S, Patarakul K, Theerawit T, Promsena P, Nantanee R, Manomaisantiphap S, Chokyakorn S, Hong L, Samija M, Montefiori DC, Gao H, Eaton A, Wijagkanalan W, Alameh MG, Weissman D, Ruxrungtham K; ChulaVac001-Phase 2 study team. Puthanakit T, et al. Sci Rep. 2024 Jan 29;14(1):2373. doi: 10.1038/s41598-023-49653-6. Sci Rep. 2024. PMID: 38287068 Free PMC article. Clinical Trial.
An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status.
Takata H, Mitchell JL, Pacheco J, Pagliuzza A, Pinyakorn S, Buranapraditkun S, Sacdalan C, Leyre L, Nathanson S, Kakazu JC, Intasan J, Prueksakaew P, Chomchey N, Phanuphak N, de Souza M, Haddad EK, Rolland M, Tovanabutra S, Vasan S, Hsu DC, Chomont N, Trautmann L; RV254/SEARCH010; RV304/SEARCH013. Takata H, et al. Among authors: chomchey n. Cell Host Microbe. 2023 Sep 13;31(9):1494-1506.e4. doi: 10.1016/j.chom.2023.08.012. Cell Host Microbe. 2023. PMID: 37708852 Free PMC article.
Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. Among authors: chomchey n. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Paradoxically Greater Persistence of HIV RNA-Positive Cells in Lymphoid Tissue When ART Is Initiated in the Earliest Stage of Infection.
Kroon E, Chottanapund S, Buranapraditkun S, Sacdalan C, Colby DJ, Chomchey N, Prueksakaew P, Pinyakorn S, Trichavaroj R, Vasan S, Manasnayakorn S, Reilly C, Helgeson E, Anderson J, David C, Zulk J, de Souza M, Tovanabutra S, Schuetz A, Robb ML, Douek DC, Phanuphak N, Haase A, Ananworanich J, Schacker TW. Kroon E, et al. Among authors: chomchey n. J Infect Dis. 2022 Jun 15;225(12):2167-2175. doi: 10.1093/infdis/jiac089. J Infect Dis. 2022. PMID: 35275599 Free PMC article.
HLA-B*57 and B*58 Associate with Predictors of Reservoir Size in an Acutely Treated HIV Cohort.
Shangguan S, Ehrenberg PK, Geretz A, Butler L, Pinyakorn S, Sriplienchan S, Sacdalan C, Chomchey N, Phanuphak N, Tovanabutra S, Vasan S, Hsu D, Thomas R. Shangguan S, et al. Among authors: chomchey n. AIDS Res Hum Retroviruses. 2023 Mar;39(3):114-118. doi: 10.1089/AID.2022.0082. Epub 2023 Jan 10. AIDS Res Hum Retroviruses. 2023. PMID: 36465028 Free PMC article.
A novel acute HIV infection staging system based on 4th generation immunoassay.
Ananworanich J, Fletcher JL, Pinyakorn S, van Griensven F, Vandergeeten C, Schuetz A, Pankam T, Trichavaroj R, Akapirat S, Chomchey N, Phanuphak P, Chomont N, Michael NL, Kim JH, de Souza M; RV254/SEARCH 010 Study Group. Ananworanich J, et al. Among authors: chomchey n. Retrovirology. 2013 May 29;10:56. doi: 10.1186/1742-4690-10-56. Retrovirology. 2013. PMID: 23718762 Free PMC article.
Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy.
Massanella M, Bakeman W, Sithinamsuwan P, Fletcher JLK, Chomchey N, Tipsuk S, Chalermchai T, Routy JP, Ananworanich J, Valcour VG, Chomont N. Massanella M, et al. Among authors: chomchey n. J Virol. 2019 Dec 12;94(1):e01174-19. doi: 10.1128/JVI.01174-19. Print 2019 Dec 12. J Virol. 2019. PMID: 31597764 Free PMC article.
Preferential and persistent impact of acute HIV-1 infection on CD4+ iNKT cells in colonic mucosa.
Paquin-Proulx D, Lal KG, Phuang-Ngern Y, Creegan M, Tokarev A, Suhkumvittaya S, Alrubayyi A, Kroon E, Pinyakorn S, Slike BM, Bolton DL, Krebs SJ, Eller LA, Sajjaweerawan C, Pagliuzza A, Chomont N, Rerknimitr R, Chomchey N, Phanuphak N, de Souza MS, Michael NL, Robb ML, Ananworanich J, Sandberg JK, Eller MA, Schuetz A; RV217; RV254/SEARCH010; RV304/SEARCH013; Study Groups. Paquin-Proulx D, et al. Among authors: chomchey n. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2104721118. doi: 10.1073/pnas.2104721118. Proc Natl Acad Sci U S A. 2021. PMID: 34753817 Free PMC article.
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