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A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke.
LeCouffe NE, Kappelhof M, Treurniet KM, Rinkel LA, Bruggeman AE, Berkhemer OA, Wolff L, van Voorst H, Tolhuisen ML, Dippel DWJ, van der Lugt A, van Es ACGM, Boiten J, Lycklama À Nijeholt GJ, Keizer K, Gons RAR, Yo LSF, van Oostenbrugge RJ, van Zwam WH, Roozenbeek B, van der Worp HB, Lo RTH, van den Wijngaard IR, de Ridder IR, Costalat V, Arquizan C, Lemmens R, Demeestere J, Hofmeijer J, Martens JM, Schonewille WJ, Vos JA, Uyttenboogaart M, Bokkers RPH, van Tuijl JH, Kortman H, Schreuder FHBM, Boogaarts HD, de Laat KF, van Dijk LC, den Hertog HM, van Hasselt BAAM, Brouwers PJAM, Bulut T, Remmers MJM, van Norden A, Imani F, Rozeman AD, Elgersma OEH, Desfontaines P, Brisbois D, Samson Y, Clarençon F, Krietemeijer GM, Postma AA, van Doormaal PJ, van den Berg R, van der Hoorn A, Beenen LFM, Nieboer D, Lingsma HF, Emmer BJ, Coutinho JM, Majoie CBLM, Roos YBWEM; MR CLEAN–NO IV Investigators. LeCouffe NE, et al. N Engl J Med. 2021 Nov 11;385(20):1833-1844. doi: 10.1056/NEJMoa2107727. N Engl J Med. 2021. PMID: 34758251 Clinical Trial.
Safety and Efficacy of Dual Thrombolytic Therapy With Mutant Prourokinase and Small Bolus Alteplase for Ischemic Stroke: A Randomized Clinical Trial.
van der Ende NAM, Roozenbeek B, Smagge LEM, Luijten SPR, Aerden LAM, Kraayeveld P, van den Wijngaard IR, Lycklama À Nijeholt GJ, den Hertog HM, Flach HZ, Postma AA, Roosendaal SD, Krietemeijer GM, Yo LSF, de Maat MPM, Nieboer D, Del Zoppo GJ, Meurer WJ, Lingsma HF, van der Lugt A, Dippel DWJ; DUMAS Investigators. van der Ende NAM, et al. JAMA Neurol. 2023 Jul 1;80(7):714-722. doi: 10.1001/jamaneurol.2023.1262. JAMA Neurol. 2023. PMID: 37213122 Free PMC article. Clinical Trial.
Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation.
van Voorst H, Hoving JW, Koopman MS, Daems JD, Peerlings D, Buskens E, Lingsma H, Marquering HA, de Jong HWAM, Berkhemer OA, van Zwam WH, van Walderveen MAA, van den Wijngaard IR, Dippel DWJ, Yoo AJ, Campbell B, Kunz WG, Majoie CB, Emmer BJ; CLEOPATRA; MR CLEAN Registry; CONTRAST Consortium Investigators. van Voorst H, et al. J Neurol Neurosurg Psychiatry. 2024 May 14;95(6):515-527. doi: 10.1136/jnnp-2023-331862. J Neurol Neurosurg Psychiatry. 2024. PMID: 38124162
Collateral-based selection for endovascular treatment of acute ischaemic stroke in the late window (MR CLEAN-LATE): 2-year follow-up of a phase 3, multicentre, open-label, randomised controlled trial in the Netherlands.
Huijberts I, Pinckaers FME, Olthuis SGH, van Kuijk SMJ, Postma AA, Boogaarts HD, Roos YBWEM, Majoie CBLM, van der Lugt A, Dippel DWJ, van Zwam WH, van Oostenbrugge RJ; MR CLEAN-LATE investigators. Huijberts I, et al. Lancet Neurol. 2024 Sep;23(9):893-900. doi: 10.1016/S1474-4422(24)00228-X. Epub 2024 Jun 20. Lancet Neurol. 2024. PMID: 38909624 Clinical Trial.
Hemorrhage rates in patients with acute ischemic stroke treated with intravenous alteplase and thrombectomy versus thrombectomy alone.
van Kranendonk KR, Kappelhof M, Bruggeman AAE, Rinkel LA, Treurniet KM, LeCouffe N, Emmer BJ, Coutinho JM, Wolff L, van Zwam WH, van Oostenbrugge RJ, van der Lugt A, Dippel DWJ, Roos YBWEM, Marquering HA, Majoie CBLM; MR CLEAN-NO IV Investigators. van Kranendonk KR, et al. J Neurointerv Surg. 2023 Nov;15(e2):e262-e269. doi: 10.1136/jnis-2022-019569. Epub 2022 Nov 17. J Neurointerv Surg. 2023. PMID: 36396434 Clinical Trial.
Effect of Intravenous Alteplase Treatment on First-Line Stent Retriever Versus Aspiration Alone During Endovascular Treatment.
Rinkel LA, Treurniet KM, Nieboer D, Kappelhof M, LeCouffe NE, Bruggeman AAE, van Zwam WH, Lycklama À Nijeholt GJ, Ghariq E, Uyttenboogaart M, Dippel DWJ, Roos YBWEM, Coutinho JM, Majoie CBLM, Emmer BJ; MR CLEAN-NO IV Investigators. Rinkel LA, et al. Stroke. 2022 Nov;53(11):3278-3288. doi: 10.1161/STROKEAHA.121.038390. Epub 2022 Jul 25. Stroke. 2022. PMID: 35876018 Clinical Trial.
Unsupervised Deep Learning for Stroke Lesion Segmentation on Follow-up CT Based on Generative Adversarial Networks.
van Voorst H, Konduri PR, van Poppel LM, van der Steen W, van der Sluijs PM, Slot EMH, Emmer BJ, van Zwam WH, Roos YBWEM, Majoie CBLM, Zaharchuk G, Caan MWA, Marquering HA; CONTRAST Consortium Collaborators; Research leaders Consortium coordinator: Imaging assessment committee Adverse event committee Outcome assessment committee Data management group Imaging data management Biomaterials and translational group Local collaborators Research nurses Study monitors Research leaders. van Voorst H, et al. AJNR Am J Neuroradiol. 2022 Aug;43(8):1107-1114. doi: 10.3174/ajnr.A7582. Epub 2022 Jul 28. AJNR Am J Neuroradiol. 2022. PMID: 35902122 Free PMC article.
Deep learning-based white matter lesion volume on CT is associated with outcome after acute ischemic stroke.
van Voorst H, Pitkänen J, van Poppel L, de Vries L, Mojtahedi M, Martou L, Emmer BJ, Roos YBWEM, van Oostenbrugge R, Postma AA, Marquering HA, Majoie CBLM, Curtze S, Melkas S, Bentley P, Caan MWA; MR CLEAN No-IV and CONTRAST consortium collaborators. van Voorst H, et al. Eur Radiol. 2024 Aug;34(8):5080-5093. doi: 10.1007/s00330-024-10584-z. Epub 2024 Jan 29. Eur Radiol. 2024. PMID: 38285103
Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study.
van Voorst H, Hoving JW, Koopman MS, Daems JD, Peerlings D, Buskens E, Lingsma HF, Beenen LFM, de Jong HWAM, Berkhemer OA, van Zwam WH, Roos YBWEM, van Walderveen MAA, van den Wijngaard I, Dippel DWJ, Yoo AJ, Campbell BCV, Kunz WG, Emmer BJ, Majoie CBLM; CLEOPATRA investigators; CONTRAST consortium; MR CLEAN Registry Investigators. van Voorst H, et al. Eur Radiol. 2024 Apr;34(4):2152-2167. doi: 10.1007/s00330-023-10119-y. Epub 2023 Sep 20. Eur Radiol. 2024. PMID: 37728778 Free PMC article.
Dual thrombolytic therapy with mutant pro-urokinase and small bolus alteplase for ischemic stroke (DUMAS): study protocol for a multicenter randomized controlled phase II trial.
van der Ende NAM, Roozenbeek B, Smagge LEM, Luijten SPR, Aerden LAM, Kraayeveld P, van den Wijngaard IR, Lycklama À Nijeholt GJ, den Hertog HM, Flach HZ, Wallace AC, Gurewich V, Del Zoppo GJ, Meurer WJ, Lingsma HF, van der Lugt A, Dippel DWJ; DUMAS Investigators. van der Ende NAM, et al. Trials. 2022 Aug 9;23(1):641. doi: 10.1186/s13063-022-06596-z. Trials. 2022. PMID: 35945566 Free PMC article.
12 results