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Page 1
Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study.
Siderowf A, Concha-Marambio L, Lafontant DE, Farris CM, Ma Y, Urenia PA, Nguyen H, Alcalay RN, Chahine LM, Foroud T, Galasko D, Kieburtz K, Merchant K, Mollenhauer B, Poston KL, Seibyl J, Simuni T, Tanner CM, Weintraub D, Videnovic A, Choi SH, Kurth R, Caspell-Garcia C, Coffey CS, Frasier M, Oliveira LMA, Hutten SJ, Sherer T, Marek K, Soto C; Parkinson's Progression Markers Initiative. Siderowf A, et al. Among authors: hutten sj. Lancet Neurol. 2023 May;22(5):407-417. doi: 10.1016/S1474-4422(23)00109-6. Lancet Neurol. 2023. PMID: 37059509 Free PMC article.
Parkinson's Progression Markers Initiative: A Milestone-Based Strategy to Monitor Parkinson's Disease Progression.
Brumm MC, Siderowf A, Simuni T, Burghardt E, Choi SH, Caspell-Garcia C, Chahine LM, Mollenhauer B, Foroud T, Galasko D, Merchant K, Arnedo V, Hutten SJ, O'Grady AN, Poston KL, Tanner CM, Weintraub D, Kieburtz K, Marek K, Coffey CS; Parkinson’s Progression Markers Initiative. Brumm MC, et al. Among authors: hutten sj. J Parkinsons Dis. 2023;13(6):899-916. doi: 10.3233/JPD-223433. J Parkinsons Dis. 2023. PMID: 37458046 Free PMC article.
Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
Gruijs da Silva LA, Simonetti F, Hutten S, Riemenschneider H, Sternburg EL, Pietrek LM, Gebel J, Dötsch V, Edbauer D, Hummer G, Stelzl LS, Dormann D. Gruijs da Silva LA, et al. Among authors: hutten s. EMBO J. 2022 Apr 19;41(8):e108443. doi: 10.15252/embj.2021108443. Epub 2022 Feb 3. EMBO J. 2022. PMID: 35112738 Free PMC article.
A proteogenomic view of Parkinson's disease causality and heterogeneity.
Kaiser S, Zhang L, Mollenhauer B, Jacob J, Longerich S, Del-Aguila J, Marcus J, Raghavan N, Stone D, Fagboyegun O, Galasko D, Dakna M, Bilican B, Dovlatyan M, Kostikova A, Li J, Peterson B, Rotte M, Sanz V, Foroud T, Hutten SJ, Frasier M, Iwaki H, Singleton A, Marek K, Crawford K, Elwood F, Messa M, Serrano-Fernandez P. Kaiser S, et al. Among authors: hutten sj. NPJ Parkinsons Dis. 2023 Feb 11;9(1):24. doi: 10.1038/s41531-023-00461-9. NPJ Parkinsons Dis. 2023. PMID: 36774388 Free PMC article.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
Kuo SH, Tasset I, Cheng MM, Diaz A, Pan MK, Lieberman OJ, Hutten SJ, Alcalay RN, Kim S, Ximénez-Embún P, Fan L, Kim D, Ko HS, Yacoubian T, Kanter E, Liu L, Tang G, Muñoz J, Sardi SP, Li A, Gan L, Cuervo AM, Sulzer D. Kuo SH, et al. Among authors: hutten sj. Sci Adv. 2022 Feb 11;8(6):eabm6393. doi: 10.1126/sciadv.abm6393. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138901 Free article.
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.
Zambusi A, Novoselc KT, Hutten S, Kalpazidou S, Koupourtidou C, Schieweck R, Aschenbroich S, Silva L, Yazgili AS, van Bebber F, Schmid B, Möller G, Tritscher C, Stigloher C, Delbridge C, Sirko S, Günes ZI, Liebscher S, Schlegel J, Aliee H, Theis F, Meiners S, Kiebler M, Dormann D, Ninkovic J. Zambusi A, et al. Among authors: hutten s. Nat Neurosci. 2022 Dec;25(12):1608-1625. doi: 10.1038/s41593-022-01199-y. Epub 2022 Nov 24. Nat Neurosci. 2022. PMID: 36424432
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Russo MJ, Orru CD, Concha-Marambio L, Giaisi S, Groveman BR, Farris CM, Holguin B, Hughson AG, LaFontant DE, Caspell-Garcia C, Coffey CS, Mollon J, Hutten SJ, Merchant K, Heym RG, Soto C, Caughey B, Kang UJ. Russo MJ, et al. Among authors: hutten sj. Acta Neuropathol Commun. 2021 Nov 6;9(1):179. doi: 10.1186/s40478-021-01282-8. Acta Neuropathol Commun. 2021. PMID: 34742348 Free PMC article.
RAN translation down.
Hutten S, Dormann D. Hutten S, et al. Nat Neurosci. 2019 Sep;22(9):1379-1380. doi: 10.1038/s41593-019-0482-4. Nat Neurosci. 2019. PMID: 31427772 No abstract available.
Mechanisms that clear mutations drive field cancerization in mammary tissue.
Ciwinska M, Messal HA, Hristova HR, Lutz C, Bornes L, Chalkiadakis T, Harkes R, Langedijk NSM, Hutten SJ, Menezes RX, Jonkers J, Prekovic S; Grand Challenge PRECISION consortium; Simons BD, Scheele CLGJ, van Rheenen J. Ciwinska M, et al. Among authors: hutten sj. Nature. 2024 Sep;633(8028):198-206. doi: 10.1038/s41586-024-07882-3. Epub 2024 Sep 4. Nature. 2024. PMID: 39232148 Free PMC article.
77 results