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The relationship between the epigenetic aging biomarker "grimage" and lung function in both the airway and blood of people living with HIV: An observational cohort study.
Hernández Cordero AI, Yang CX, Yang J, Li X, Horvath S, Shaipanich T, MacIsaac J, Lin D, McEwen L, Kobor MS, Guillemi S, Harris M, Lam W, Lam S, Obeidat M, Novak RM, Hudson F, Klinker H, Dharan N, Montaner J, Man SFP, Kunisaki K, Sin DD, Leung JM; INSIGHT START Pulmonary and Genomic Substudy Groups. Hernández Cordero AI, et al. EBioMedicine. 2022 Sep;83:104206. doi: 10.1016/j.ebiom.2022.104206. Epub 2022 Aug 6. EBioMedicine. 2022. PMID: 35944348 Free PMC article.
DNA methylation is associated with airflow obstruction in patients living with HIV.
Hernandez Cordero AI, Yang CX, Obeidat M, Yang J, MacIsaac J, McEwen L, Lin D, Kobor M, Novak R, Hudson F, Klinker H, Dharan N, Man SP, Sin DD, Kunisaki K, Leung J; INSIGHT START Pulmonary and Genomic Substudy Groups. Hernandez Cordero AI, et al. Thorax. 2021 May;76(5):448-455. doi: 10.1136/thoraxjnl-2020-215866. Epub 2020 Dec 18. Thorax. 2021. PMID: 33443234 Free PMC article. Clinical Trial.