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Discontinuation of L-asparaginase and poor response to prednisolone are associated with poor outcome of ETV6-RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia.
Usami I, Imamura T, Takahashi Y, Suenobu SI, Hasegawa D, Hashii Y, Deguchi T, Hori T, Shimada A, Kato K, Ito E, Moriya-Saito A, Kawasaki H, Hori H, Yumura-Yagi K, Hara J, Sato A, Horibe K; Japan Association of Childhood Leukemia Study Group (JACLS). Usami I, et al. Int J Hematol. 2019 Apr;109(4):477-482. doi: 10.1007/s12185-019-02599-w. Epub 2019 Jan 28. Int J Hematol. 2019. PMID: 30689137
Risk-adjusted therapy for pediatric non-T cell ALL improves outcomes for standard risk patients: results of JACLS ALL-02.
Hasegawa D, Imamura T, Yumura-Yagi K, Takahashi Y, Usami I, Suenobu SI, Nishimura S, Suzuki N, Hashii Y, Deguchi T, Moriya-Saito A, Kato K, Kosaka Y, Hirayama M, Iguchi A, Kawasaki H, Hori H, Sato A, Kudoh T, Nakahata T, Oda M, Hara J, Horibe K; Japan Association of Childhood Leukemia Study Group (JACLS). Hasegawa D, et al. Blood Cancer J. 2020 Feb 27;10(2):23. doi: 10.1038/s41408-020-0287-4. Blood Cancer J. 2020. PMID: 32107374 Free PMC article. Clinical Trial.
The incidence of symptomatic osteonecrosis is similar between Japanese children and children in Western countries with acute lymphoblastic leukaemia treated with a Berlin-Frankfurt-Münster (BFM)95-based protocol.
Moriya K, Imamura T, Katayama S, Kaino A, Okamoto K, Yokoyama N, Uemura S, Kitazawa H, Sekimizu M, Hiramatsu H, Usami I, Ishida H, Hasegawa D, Hama A, Moriya-Saito A, Sato A, Sasahara Y, Suenobu S, Horibe K, Hara J; Japan Association of Childhood Leukemia Study Group (JACLS). Moriya K, et al. Br J Haematol. 2022 Mar;196(5):1257-1261. doi: 10.1111/bjh.17988. Epub 2021 Dec 8. Br J Haematol. 2022. PMID: 34879431