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Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Takeshita M, Fukuyama H, Kamada K, Matsumoto T, Makino-Okamura C, Lin Q, Sakuma M, Kawahara E, Yamazaki I, Uchikubo-Kamo T, Tomabechi Y, Hanada K, Hisano T, Moriyama S, Takahashi Y, Ito M, Imai M, Maemura T, Furusawa Y, Yamayoshi S, Kawaoka Y, Shirouzu M, Ishii M, Saya H, Kondo Y, Kaneko Y, Suzuki K, Fukunaga K, Takeuchi T; Keio Donner Project. Takeshita M, et al. iScience. 2023 Jun 16;26(6):106955. doi: 10.1016/j.isci.2023.106955. Epub 2023 May 25. iScience. 2023. PMID: 37288342 Free PMC article.
Pro108Ser mutation of SARS-CoV-2 3CLpro reduces the enzyme activity and ameliorates the clinical severity of COVID-19.
Abe K, Kabe Y, Uchiyama S, Iwasaki YW, Ishizu H, Uwamino Y, Takenouchi T, Uno S, Ishii M, Maruno T, Noda M, Murata M, Hasegawa N, Saya H, Kitagawa Y, Fukunaga K, Amagai M, Siomi H, Suematsu M, Kosaki K; Keio Donner Project. Abe K, et al. Sci Rep. 2022 Jan 25;12(1):1299. doi: 10.1038/s41598-022-05424-3. Sci Rep. 2022. PMID: 35079088 Free PMC article.
Dynamics of antibody titers and cellular immunity among Japanese healthcare workers during the 6 months after receiving two doses of BNT162b2 mRNA vaccine.
Uwamino Y, Kurafuji T, Takato K, Sakai A, Tanabe A, Noguchi M, Yatabe Y, Arai T, Ohno A, Tomita Y, Shibata A, Yokota H, Yamasawa W, Namkoong H, Sato Y, Hasegawa N, Wakui M, Murata M; Keio Donner Project Team. Uwamino Y, et al. Vaccine. 2022 Jul 30;40(32):4538-4543. doi: 10.1016/j.vaccine.2022.06.016. Epub 2022 Jun 17. Vaccine. 2022. PMID: 35718591 Free PMC article.
Clinical Utility of SARS-CoV-2 Whole Genome Sequencing in Deciphering Source of Infection.
Takenouchi T, Iwasaki YW, Harada S, Ishizu H, Uwamino Y, Uno S, Osada A, Abe K, Hasegawa N, Murata M, Takebayashi T, Fukunaga K, Saya H, Kitagawa Y, Amagai M, Siomi H, Kosaki K; Keio Donner Project. Takenouchi T, et al. J Hosp Infect. 2020 Oct 24;107:40-4. doi: 10.1016/j.jhin.2020.10.014. Online ahead of print. J Hosp Infect. 2020. PMID: 34756867 Free PMC article.
Young age, female sex, and presence of systemic adverse reactions are associated with high post-vaccination antibody titer after two doses of BNT162b2 mRNA SARS-CoV-2 vaccination: An observational study of 646 Japanese healthcare workers and university staff.
Uwamino Y, Kurafuji T, Sato Y, Tomita Y, Shibata A, Tanabe A, Yatabe Y, Noguchi M, Arai T, Ohno A, Yokota H, Yamasawa W, Uno S, Nishimura T, Hasegawa N, Saya H, Wakui M, Murata M; Keio Donner Project Team. Uwamino Y, et al. Vaccine. 2022 Feb 11;40(7):1019-1025. doi: 10.1016/j.vaccine.2022.01.002. Epub 2022 Jan 7. Vaccine. 2022. PMID: 35033389 Free PMC article.
SARS-CoV-2 Infection among Medical Institution Faculty and Healthcare Workers in Tokyo, Japan.
Nishimura T, Uwamino Y, Uno S, Kashimura S, Shiraki T, Kurafuji T, Morita M, Noguchi M, Azegami T, Yamada-Goto N, Murai-Takeda A, Yokoyama H, Kuwabara K, Kato S, Matsumoto M, Hirata A, Iida M, Harada S, Ishizaka T, Misawa K, Murata M, Saya H, Amagai M, Kitagawa Y, Takeuchi T, Mori M, Takebayashi T, Hasegawa N; Keio Donner Project Team. Nishimura T, et al. Intern Med. 2021 Aug 15;60(16):2569-2575. doi: 10.2169/internalmedicine.7033-21. Epub 2021 Jun 19. Intern Med. 2021. PMID: 34148952 Free PMC article.
18 results