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Page 1
Development of the Crohn's disease digestive damage score, the Lemann score.
Pariente B, Cosnes J, Danese S, Sandborn WJ, Lewin M, Fletcher JG, Chowers Y, D'Haens G, Feagan BG, Hibi T, Hommes DW, Irvine EJ, Kamm MA, Loftus EV Jr, Louis E, Michetti P, Munkholm P, Oresland T, Panés J, Peyrin-Biroulet L, Reinisch W, Sands BE, Schoelmerich J, Schreiber S, Tilg H, Travis S, van Assche G, Vecchi M, Mary JY, Colombel JF, Lémann M. Pariente B, et al. Inflamm Bowel Dis. 2011 Jun;17(6):1415-22. doi: 10.1002/ibd.21506. Epub 2010 Nov 28. Inflamm Bowel Dis. 2011. PMID: 21560202 Free PMC article.
This instrument, called the Crohn's Disease Digestive Damage Score (the Lemann score), should take into account damage location, severity, extent, progression, and reversibility, as measured by diagnostic imaging modalities and the history of surgical resection. ...At leas …
This instrument, called the Crohn's Disease Digestive Damage Score (the Lemann score), should take into account damage location, seve …
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H; International IBD Genetics Consortium (IIBDGC); Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parke… See abstract for full author list ➔ Jostins L, et al. Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582. Nature. 2012. PMID: 23128233 Free PMC article.
Lemann Index for assessing bowel damage in Crohn's disease: a real world study.
Prado E, Law CCY, Rowan C, Osman A, Gore E, Ballard DH, Ludwig DR, Tsai R, Gergely M, Geahchan A, Taouli B, Abboud G, Altinmakas E, Rajauria P, Colombel JF, Ungaro RC, Deepak P. Prado E, et al. J Crohns Colitis. 2024 Jun 27:jjae102. doi: 10.1093/ecco-jcc/jjae102. Online ahead of print. J Crohns Colitis. 2024. PMID: 38935558
BACKGROUND & AIMS: The Lemann Index (LI), an endpoint to measure cumulative structural bowel damage in Crohn's disease (CD), has been recently updated and validated. ...
BACKGROUND & AIMS: The Lemann Index (LI), an endpoint to measure cumulative structural bowel damage in Crohn's disease (CD), has …
Infliximab, azathioprine, or combination therapy for Crohn's disease.
Colombel JF, Sandborn WJ, Reinisch W, Mantzaris GJ, Kornbluth A, Rachmilewitz D, Lichtiger S, D'Haens G, Diamond RH, Broussard DL, Tang KL, van der Woude CJ, Rutgeerts P; SONIC Study Group. Colombel JF, et al. N Engl J Med. 2010 Apr 15;362(15):1383-95. doi: 10.1056/NEJMoa0904492. N Engl J Med. 2010. PMID: 20393175 Free article. Clinical Trial.
Preventing Collateral Damage in Crohn's Disease: The Lemann Index.
Fiorino G, Bonifacio C, Peyrin-Biroulet L, Danese S. Fiorino G, et al. J Crohns Colitis. 2016 Apr;10(4):495-500. doi: 10.1093/ecco-jcc/jjv240. Epub 2016 Jan 7. J Crohns Colitis. 2016. PMID: 26744441 Free PMC article. Review.
Similar to the joint damage in rheumatoid arthritis, bowel damage has also emerged as a new endpoint in disease-modification trials such as the REACT trial. Recently, the Lemann Index [LI] has been developed to measure CD-related bowel damage, and to assess damage progress …
Similar to the joint damage in rheumatoid arthritis, bowel damage has also emerged as a new endpoint in disease-modification trials such as …
Lemann Index at Diagnosis Predicts the Risk of Early Surgery in Crohn's Disease.
Liu W, Zhou W, Xiang J, Cao Q, Zhu J, Qi W, Chen P, Xie Q. Liu W, et al. Dis Colon Rectum. 2018 Feb;61(2):207-213. doi: 10.1097/DCR.0000000000000930. Dis Colon Rectum. 2018. PMID: 29337776
Lemann index was much higher in the surgery group (5.3 vs 2.6; p < 0.001). On tertiles of the Lemann index, the frequency of surgery grew (2.8%, 9.9%, and 55.7%; p < 0.001) as the Lemann index increased. The receiver operating characteristic curve was c
Lemann index was much higher in the surgery group (5.3 vs 2.6; p < 0.001). On tertiles of the Lemann index, the frequency o
Validation and Update of the Lemann Index to Measure Cumulative Structural Bowel Damage in Crohn's Disease.
Pariente B, Torres J, Burisch J, Arebi N, Barberio B, Duricova D, Ellul P, Goldis A, Kaimakliotis I, Katsanos K, Krznaric Ž, McNamara D, Pedersen N, Sebastian S, Azahaf M, Weimers P, Lung P, Lacognata C, Horak M, Christodoulou D, Domislovic V, Murphy I, Lambert J, Ungaro R, Colombel JF, Mary JY. Pariente B, et al. Gastroenterology. 2021 Sep;161(3):853-864.e13. doi: 10.1053/j.gastro.2021.05.049. Epub 2021 May 28. Gastroenterology. 2021. PMID: 34052277 Free PMC article.
BACKGROUND & AIMS: The Lemann Index is a tool measuring cumulative structural bowel damage in Crohn's disease (CD). ...Simple linear regressions of investigator damage evaluations on their corresponding Lemann Index were studied, as well as calibration plots. Fi …
BACKGROUND & AIMS: The Lemann Index is a tool measuring cumulative structural bowel damage in Crohn's disease (CD). ...Simple lin …
Lemann Index for Assessment of Crohn's Disease: Correlation with the Quality of Life, Endoscopic Disease Activity, Magnetic Resonance Index of Activity and C- Reactive Protein.
Straksyte V, Kiudelis G, Gineikiene I, Janciauskas D, Basevicius A, Lukosevicius S, Kupcinskas L. Straksyte V, et al. Open Med (Wars). 2019 Nov 7;14:785-791. doi: 10.1515/med-2019-0092. eCollection 2019. Open Med (Wars). 2019. PMID: 31737782 Free PMC article.
MR-EC was used to evaluate the Magnetic Resonance Index of Activity (MaRIA- global (G)) and the Lemann Index (LI). The CD Endoscopic Index of Severity (CDEIS) was used to score the endoscopic activity of the disease. ...
MR-EC was used to evaluate the Magnetic Resonance Index of Activity (MaRIA- global (G)) and the Lemann Index (LI). The CD Endoscopic …
438 results