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29 results

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Page 1
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.
Berard AR, Brubaker DK, Birse K, Lamont A, Mackelprang RD, Noël-Romas L, Perner M, Hou X, Irungu E, Mugo N, Knodel S, Muwonge TR, Katabira E, Hughes SM, Levy C, Calienes FL, Lauffenburger DA, Baeten JM, Celum C, Hladik F, Lingappa J, Burgener AD. Berard AR, et al. Among authors: noel romas l. Cell Rep. 2023 May 30;42(5):112474. doi: 10.1016/j.celrep.2023.112474. Epub 2023 May 6. Cell Rep. 2023. PMID: 37149863 Free PMC article.
Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data.
Hughes SM, Levy CN, Katz R, Lokken EM, Anahtar MN, Hall MB, Bradley F, Castle PE, Cortez V, Doncel GF, Fichorova R, Fidel PL Jr, Fowke KR, Francis SC, Ghosh M, Hwang LY, Jais M, Jespers V, Joag V, Kaul R, Kyongo J, Lahey T, Li H, Makinde J, McKinnon LR, Moscicki AB, Novak RM, Patel MV, Sriprasert I, Thurman AR, Yegorov S, Mugo NR, Roxby AC, Micks E, Hladik F; Consortium for Assessing Immunity Across the Menstrual Cycle. Hughes SM, et al. BMC Med. 2022 Oct 5;20(1):353. doi: 10.1186/s12916-022-02532-9. BMC Med. 2022. PMID: 36195867 Free PMC article.
Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.
Farr Zuend C, Lamont A, Noel-Romas L, Knodel S, Birse K, Kratzer K, McQueen P, Perner M, Ayele H, Mutch S, Berard AR, Schellenberg JJ, Senturk F, McCorrister S, Westmacott G, Mulhall F, Sandberg B, Yu A, Burnett M, Poliquin V, Burgener AD. Farr Zuend C, et al. Among authors: noel romas l. Microbiome. 2023 Jul 25;11(1):159. doi: 10.1186/s40168-023-01594-y. Microbiome. 2023. PMID: 37491398 Free PMC article.
Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection.
Ferrari B, Da Silva AC, Liu KH, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive C, Pacheco Sanchez G, Retuerto M, Sharma AA, Ghneim K, Noel-Romas L, Rodriguez B, Ghannoum MA, Hunt PP, Deeks SG, Burgener AD, Jones DP, Dobre MA, Marconi VC, Sekaly RP, Younes SA. Ferrari B, et al. Among authors: noel romas l. J Clin Invest. 2022 May 2;132(9):e149571. doi: 10.1172/JCI149571. J Clin Invest. 2022. PMID: 35316209 Free PMC article.
Systems analysis reveals differential expression of endocervical genes in African women randomized to DMPA-IM, LNG implant or cu-IUD.
Gupta PM, Balle C, Tharp GK, Nelson SA, Gasper MA, Brown B, Alisoltani A, Onono M, Palanee-Phillips T, Nair G, Ayele H, Noel-Romas L, Passmore JS, Burgener AD, Heffron R, Jaspan HB, Bosinger SE. Gupta PM, et al. Among authors: noel romas l. Clin Immunol. 2023 Oct;255:109750. doi: 10.1016/j.clim.2023.109750. Epub 2023 Sep 3. Clin Immunol. 2023. PMID: 37660744 Free PMC article. Clinical Trial.
Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases.
Flynn JK, Ortiz AM, Vujkovic-Cvijin I, Welles HC, Simpson J, Castello Casta FM, Yee DS, Rahmberg AR, Brooks KL, De Leon M, Knodel S, Birse K, Noel-Romas L, Deewan A, Belkaid Y, Burgener A, Brenchley JM. Flynn JK, et al. Among authors: noel romas l. Mucosal Immunol. 2024 Oct;17(5):1089-1101. doi: 10.1016/j.mucimm.2024.07.008. Epub 2024 Jul 31. Mucosal Immunol. 2024. PMID: 39089468 Free PMC article.
Gut microbiome signatures linked to HIV-1 reservoir size and viremia control.
Borgognone A, Noguera-Julian M, Oriol B, Noël-Romas L, Ruiz-Riol M, Guillén Y, Parera M, Casadellà M, Duran C, Puertas MC, Català-Moll F, De Leon M, Knodel S, Birse K, Manzardo C, Miró JM, Clotet B, Martinez-Picado J, Moltó J, Mothe B, Burgener A, Brander C, Paredes R; BCN02 Study Group. Borgognone A, et al. Among authors: noel romas l. Microbiome. 2022 Apr 11;10(1):59. doi: 10.1186/s40168-022-01247-6. Microbiome. 2022. PMID: 35410461 Free PMC article. Clinical Trial.
Non-Lactobacillus-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acquisition.
Wang Y, Noël-Romas L, Perner M, Knodel S, Molatlhegi R, Hoger S, Birse K, Zuend CF, McKinnon LR, Burgener AD. Wang Y, et al. Among authors: noel romas l. Clin Infect Dis. 2023 Apr 17;76(8):1372-1381. doi: 10.1093/cid/ciac938. Clin Infect Dis. 2023. PMID: 36504254 Free PMC article. Clinical Trial.
A Description of the THRIVE (The Study of Host-Bacterial Relationships and Immune Function in Different Vaginal Environments) Bacterial Vaginosis Observational Study.
Berard AR, Knodel S, Zuend CF, Noël-Romas L, Birse KD, McQueen P, De Leon M, Kratzer K, Taylor OA, Bailey S, Pymar H, Burgener AD, Poliquin V. Berard AR, et al. Among authors: noel romas l. J Obstet Gynaecol Can. 2024 Dec;46(12):102667. doi: 10.1016/j.jogc.2024.102667. Epub 2024 Oct 2. J Obstet Gynaecol Can. 2024. PMID: 39362489 Free article.
Nonoptimal bacteria species induce neutrophil-driven inflammation and barrier disruption in the female genital tract.
Costa-Fujishima M, Yazdanpanah A, Horne S, Lamont A, Lopez P, Farr Zuend C, Birse K, Taverner M, Greenslade R, Abou M, Noel-Romas L, Abrenica B, Ajibola O, Ikeogu N, Su RC, McKinnon LR, Pymar H, Poliquin V, Berard AR, Burgener AD, Murooka TT. Costa-Fujishima M, et al. Among authors: noel romas l. Mucosal Immunol. 2023 Jun;16(3):341-356. doi: 10.1016/j.mucimm.2023.04.001. Epub 2023 Apr 29. Mucosal Immunol. 2023. PMID: 37121385 Free article.
29 results