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Page 1
The accuracy of the THIM wearable device for estimating sleep onset latency.
Scott H, Whitelaw A, Canty A, Lovato N, Lack L. Scott H, et al. J Clin Sleep Med. 2021 May 1;17(5):973-981. doi: 10.5664/jcsm.9070. J Clin Sleep Med. 2021. PMID: 33438575 Free PMC article.

There were moderate correlations between PSG and THIM on both nights [r((s)) > .57, P < .001]. In 23.74% of trials, PSG sleep onset could not be determined before THIM ended the trial. With a revised THIM algorithm in study 2, there was no significant d

There were moderate correlations between PSG and THIM on both nights [r((s)) > .57, P < .001]. In 23.74% of trials, PSG sleep o

The Development and Accuracy of the THIM Wearable Device for Estimating Sleep and Wakefulness.
Scott H, Lovato N, Lack L. Scott H, et al. Nat Sci Sleep. 2021 Jan 12;13:39-53. doi: 10.2147/NSS.S287048. eCollection 2021. Nat Sci Sleep. 2021. PMID: 33469399 Free PMC article.
INTRODUCTION: THIM is a new wearable device worn on the finger that can passively monitor sleep and wakefulness overnight using actigraphy. ...Future research will examine the accuracy of THIM for monitoring sleep in people with insomnia....
INTRODUCTION: THIM is a new wearable device worn on the finger that can passively monitor sleep and wakefulness overnight using actig …
Alpha lipoic acid ameliorates THIM-induced prefrontal cell loss and abnormal enzymatically contents in the developing rat.
Noshadian M, Namvarpour Z, Amini A, Raoofi A, Atabati H, Sadeghi Y, Aliaghaei A, Abdollahifar MA. Noshadian M, et al. J Chem Neuroanat. 2020 Jan;103:101727. doi: 10.1016/j.jchemneu.2019.101727. Epub 2019 Nov 15. J Chem Neuroanat. 2020. PMID: 31740419
Today, it was somewhat clear that Thimerosal (THIM) is a neurotoxicant preservative. We aimed to use of a suitable agent for preventing of THIM side effects on brain. ...Male Wistar rats (n = 60) were randomly distributed into five groups: 1- THIM group; this …
Today, it was somewhat clear that Thimerosal (THIM) is a neurotoxicant preservative. We aimed to use of a suitable agent for preventi …
Regulation of the ThiM riboswitch is facilitated by the trapped structure formed during transcription of the wild-type sequence.
Du C, Wang Y, Gong S. Du C, et al. FEBS Lett. 2021 Nov;595(22):2816-2828. doi: 10.1002/1873-3468.14202. Epub 2021 Oct 30. FEBS Lett. 2021. PMID: 34644399 Free article.
The ThiM riboswitch from Escherichia coli is a typical mRNA device that modulates downstream gene expression by sensing TPP. ...Instead of stabilities of the genetic ON and OFF states, the transcription rate, pause, and ligand levels are combined to affect the ThiM
The ThiM riboswitch from Escherichia coli is a typical mRNA device that modulates downstream gene expression by sensing TPP. ...Inste …
Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.
Chen Y, Wang L, Shang F, Liu W, Lan J, Chen J, Ha NC, Quan C, Nam KH, Xu Y. Chen Y, et al. Biochem Biophys Res Commun. 2019 Oct 20;518(3):513-518. doi: 10.1016/j.bbrc.2019.08.086. Epub 2019 Aug 19. Biochem Biophys Res Commun. 2019. PMID: 31439375
In bacterial thiamin synthesis and salvage pathways, the 5-(hydroxyethyl)-methylthiazole kinase (ThiM) is essential in the pathway forming TPP. Thus, ThiM is considered to be an attractive antibacterial drug target. ...The structures will provide new insight into th …
In bacterial thiamin synthesis and salvage pathways, the 5-(hydroxyethyl)-methylthiazole kinase (ThiM) is essential in the pathway fo …
The thiM locus and its relation to phosphorylation of hydroxyethylthiazole in Escherichia coli.
Mizote T, Nakayama H. Mizote T, et al. J Bacteriol. 1989 Jun;171(6):3228-32. doi: 10.1128/jb.171.6.3228-3232.1989. J Bacteriol. 1989. PMID: 2542220 Free PMC article.
By conjugation and P1 transduction, a gene governing hydroxyethylthiazole kinase activity, for which we propose the designation thiM, was mapped on the chromosome close to thiD, a gene specifying phosphomethylpyrimidine kinase activity....
By conjugation and P1 transduction, a gene governing hydroxyethylthiazole kinase activity, for which we propose the designation thiM, …
Effects of Treadmill Exercise on Social Behavior in Rats Exposed to Thimerosal with Respect to the Hippocampal Level of GluN1, GluN2A, and GluN2B.
Alipour V, Shabani R, Rahmani-Nia F, Vaseghi S, Nasehi M, Zarrindast MR. Alipour V, et al. J Mol Neurosci. 2022 Jun;72(6):1345-1357. doi: 10.1007/s12031-022-02027-5. Epub 2022 May 21. J Mol Neurosci. 2022. PMID: 35597884
THIM increased the expression of GluN2B, while exercise 1 reversed this effect. All exercise protocols increased the expression of GluN2A, and exercises 2 and 1 + 2 increased the expression of GluN1 in THIM rats. In conclusion, both THIM and exercise impaired
THIM increased the expression of GluN2B, while exercise 1 reversed this effect. All exercise protocols increased the expression of Gl
Conformational changes in the expression domain of the Escherichia coli thiM riboswitch.
Rentmeister A, Mayer G, Kuhn N, Famulok M. Rentmeister A, et al. Nucleic Acids Res. 2007;35(11):3713-22. doi: 10.1093/nar/gkm300. Epub 2007 May 21. Nucleic Acids Res. 2007. PMID: 17517779 Free PMC article.
The thiM riboswitch contains an aptamer domain that adaptively binds the coenzyme thiamine pyrophosphate (TPP). ...The recently solved crystal structures of the aptamer domains of the thiM riboswitches in complex with TPP revealed how TPP stabilizes secondary and te …
The thiM riboswitch contains an aptamer domain that adaptively binds the coenzyme thiamine pyrophosphate (TPP). ...The recently solve …
Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides.
Rentmeister A, Mayer G, Kuhn N, Famulok M. Rentmeister A, et al. Biol Chem. 2008 Feb;389(2):127-34. doi: 10.1515/BC.2008.012. Biol Chem. 2008. PMID: 18163882
Abstract Bacterial thiM riboswitches contain aptamer domains that bind the metabolite thiamine pyrophosphate (TPP). ...Here, we report identification of three putative thiM riboswitches from different bacteria and analysis of their secondary structures. ...
Abstract Bacterial thiM riboswitches contain aptamer domains that bind the metabolite thiamine pyrophosphate (TPP). ...Here, we repor …
929 results