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Page 1
A Comparative Assessment Study of Known Small-molecule GPVI Modulators.
Foster H, Wilson C, Gauer JS, Xu RG, Howard MJ, Manfield IW, Ariëns R, Naseem K, Vidler LR, Philippou H, Foster R. Foster H, et al. Among authors: vidler lr. ACS Med Chem Lett. 2022 Jan 20;13(2):171-181. doi: 10.1021/acsmedchemlett.1c00414. eCollection 2022 Feb 10. ACS Med Chem Lett. 2022. PMID: 35178172 Free PMC article.
Creating a Virtual Assistant for Medicinal Chemistry.
Vidler LR, Baumgartner MP. Vidler LR, et al. ACS Med Chem Lett. 2019 Jun 7;10(7):1051-1055. doi: 10.1021/acsmedchemlett.9b00151. eCollection 2019 Jul 11. ACS Med Chem Lett. 2019. PMID: 31312407 Free PMC article.
Design of Novel Series of Antimalarial PMX Inhibitors with Increased Half-Life via Molecular Property Optimization.
Sakata K, Lowe MA, Xuan M, Bruffaerts J, Stasi LP, Lallemand B, Cardenas A, Taylor RD, Vidler LR, King L, Valentin JP, Laleu B, de Haro T. Sakata K, et al. Among authors: vidler lr. ACS Med Chem Lett. 2023 Oct 20;14(11):1582-1588. doi: 10.1021/acsmedchemlett.3c00404. eCollection 2023 Nov 9. ACS Med Chem Lett. 2023. PMID: 37974949 Free PMC article.
Design and Synthesis of 56 Shape-Diverse 3D Fragments.
Downes TD, Jones SP, Klein HF, Wheldon MC, Atobe M, Bond PS, Firth JD, Chan NS, Waddelove L, Hubbard RE, Blakemore DC, De Fusco C, Roughley SD, Vidler LR, Whatton MA, Woolford AJ, Wrigley GL, O'Brien P. Downes TD, et al. Among authors: vidler lr. Chemistry. 2020 Jul 22;26(41):8969-8975. doi: 10.1002/chem.202001123. Epub 2020 Jul 8. Chemistry. 2020. PMID: 32315100 Free PMC article.
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates.
Jones SP, Firth JD, Wheldon MC, Atobe M, Hubbard RE, Blakemore DC, De Fusco C, Lucas SCC, Roughley SD, Vidler LR, Whatton MA, Woolford AJ, Wrigley GL, O'Brien P. Jones SP, et al. Among authors: vidler lr. RSC Med Chem. 2022 Oct 11;13(12):1614-1620. doi: 10.1039/d2md00239f. eCollection 2022 Dec 14. RSC Med Chem. 2022. PMID: 36545433 Free PMC article.
21 results