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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1948 1
1949 1
1950 1
1951 1
1953 3
1954 1
1955 4
1956 2
1957 5
1958 2
1959 2
1961 1
1962 2
1963 9
1964 7
1965 10
1966 7
1967 7
1968 18
1969 19
1970 8
1971 23
1972 31
1973 31
1974 40
1975 70
1976 93
1977 103
1978 82
1979 107
1980 125
1981 158
1982 171
1983 231
1984 262
1985 322
1986 360
1987 325
1988 310
1989 417
1990 415
1991 466
1992 514
1993 553
1994 514
1995 526
1996 498
1997 570
1998 530
1999 497
2000 523
2001 551
2002 547
2003 513
2004 538
2005 566
2006 489
2007 559
2008 605
2009 713
2010 549
2011 357
2012 430
2013 430
2014 436
2015 437
2016 409
2017 399
2018 424
2019 438
2020 517
2021 450
2022 379
2023 374
2024 380
2025 6

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19,307 results

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Page 1
New Concepts and Mechanisms of Platelet Activation Signaling.
Estevez B, Du X. Estevez B, et al. Physiology (Bethesda). 2017 Mar;32(2):162-177. doi: 10.1152/physiol.00020.2016. Physiology (Bethesda). 2017. PMID: 28228483 Free PMC article. Review.
Upon blood vessel injury, platelets are exposed to adhesive proteins in the vascular wall and soluble agonists, which initiate platelet activation, leading to formation of hemostatic thrombi. ...Platelet activation requires intracellular signal transdu …
Upon blood vessel injury, platelets are exposed to adhesive proteins in the vascular wall and soluble agonists, which initiate …
Platelet intrinsic apoptosis.
Josefsson EC. Josefsson EC. Thromb Res. 2023 Nov;231:206-213. doi: 10.1016/j.thromres.2022.11.024. Epub 2022 Dec 12. Thromb Res. 2023. PMID: 36739256 Free article. Review.
In a healthy individual, the lifespan of most platelets is tightly regulated by intrinsic, or mitochondrial, apoptosis. This is a special form of programmed cell death governed by the BCL-2 family of proteins, where the prosurvival protein BCL-X(L) maintains plat …
In a healthy individual, the lifespan of most platelets is tightly regulated by intrinsic, or mitochondrial, apoptosis. This is a spe …
Gamma and X-ray irradiation do not affect the in vitro quality of refrigerated apheresis platelets in platelet additive solution (PAS-E).
Johnson L, Roan C, Costa M, Aung HH, Marks DC. Johnson L, et al. Transfusion. 2022 Aug;62 Suppl 1:S43-S52. doi: 10.1111/trf.16983. Epub 2022 Jun 24. Transfusion. 2022. PMID: 35748661
On day 2, one of each component was gamma or X-ray irradiated or remained non-irradiated. Platelets were tested over 21 days. RESULTS: The platelet concentration decreased by approximately 20% in all groups during 21 days of storage (p > .05). ...DISCUSSIO …
On day 2, one of each component was gamma or X-ray irradiated or remained non-irradiated. Platelets were tested over 21 days. …
Thromboinflammation and the Role of Platelets.
Mack A, Vanden Hoek T, Du X. Mack A, et al. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1175-1180. doi: 10.1161/ATVBAHA.124.320149. Epub 2024 May 22. Arterioscler Thromb Vasc Biol. 2024. PMID: 38776384 Free article. Review. No abstract available.
The platelet as a model system for the acute actions of nuclear receptors.
Bishop-Bailey D. Bishop-Bailey D. Steroids. 2010 Aug-Sep;75(8-9):570-5. doi: 10.1016/j.steroids.2009.09.005. Epub 2009 Sep 22. Steroids. 2010. PMID: 19778546 Review.
Recently, a number of nuclear receptors have been found present in human platelets, including the receptors for sex steroids, and glucocorticoids, along with peroxisome proliferator-activated receptors (PPAR)s and retinoid X receptors (RXR)s. Although the platele …
Recently, a number of nuclear receptors have been found present in human platelets, including the receptors for sex steroids, and glu …
Establishing biological reference intervals for novel platelet parameters (immature platelet fraction, high immature platelet fraction, platelet distribution width, platelet large cell ratio, platelet-X, plateletcrit, and platelet distribution width) and their correlations among each other.
Sachdev R, Tiwari AK, Goel S, Raina V, Sethi M. Sachdev R, et al. Indian J Pathol Microbiol. 2014 Apr-Jun;57(2):231-5. doi: 10.4103/0377-4929.134676. Indian J Pathol Microbiol. 2014. PMID: 24943755
RESULTS: The normal range for various parameters was platelet count: 150-520 10(3)/cu mm, immature platelet fraction (IPF): 0.3-8.7%, platelet distribution width (PDW): 8.3-25.0 fL, mean platelet volume (MPV): 8.6-15.5 fL, plateletcrit (PCT): 0.15-0.62 …
RESULTS: The normal range for various parameters was platelet count: 150-520 10(3)/cu mm, immature platelet fraction (IPF): 0. …
Genetic loci associated with platelet traits and platelet disorders.
Bunimov N, Fuller N, Hayward CP. Bunimov N, et al. Semin Thromb Hemost. 2013 Apr;39(3):291-305. doi: 10.1055/s-0033-1334466. Epub 2013 Mar 6. Semin Thromb Hemost. 2013. PMID: 23468379 Review.
Moreover, the genes altered by disease-causing mutations have now been identified for several platelet disorders, including X-linked recessive, autosomal dominant, and autosomal recessive platelet disorders. Some mutations that cause inherited platelet …
Moreover, the genes altered by disease-causing mutations have now been identified for several platelet disorders, including X- …
Platelet life span and apoptosis.
Josefsson EC, White MJ, Dowling MR, Kile BT. Josefsson EC, et al. Methods Mol Biol. 2012;788:59-71. doi: 10.1007/978-1-61779-307-3_5. Methods Mol Biol. 2012. PMID: 22130700
Like many nucleated mammalian cells, the life and death of the anucleate platelet is regulated by Bcl-2 family proteins. Platelets depend on Bcl-x(L) for survival. ...Perturbations in the platelet apoptosis program lead to changes in platelet li …
Like many nucleated mammalian cells, the life and death of the anucleate platelet is regulated by Bcl-2 family proteins. Platelets …
Novel platelet products, substitutes and alternatives.
Blajchman MA. Blajchman MA. Transfus Clin Biol. 2001 Jun;8(3):267-71. doi: 10.1016/s1246-7820(01)00127-6. Transfus Clin Biol. 2001. PMID: 11499975 Review.
Efforts to overcome these shortcomings have resulted in an array of novel platelet products, substitutes, and alternatives; which are currently at various stages of development. This review summarizes the recent developments in the frozen and cold storage of platelets …
Efforts to overcome these shortcomings have resulted in an array of novel platelet products, substitutes, and alternatives; which are …
Factor X bound to the surface of activated human platelets is preferentially activated by platelet-bound factor IXa.
Scandura JM, Walsh PN. Scandura JM, et al. Biochemistry. 1996 Jul 9;35(27):8903-13. doi: 10.1021/bi9525031. Biochemistry. 1996. PMID: 8688426
Factor X is a zymogen in the blood coagulation system which is activated by the serine protease, factor IXa, in a reaction that is promoted by the presence of stimulated platelets. ...These findings suggest that platelet-bound zymogen factor X r …
Factor X is a zymogen in the blood coagulation system which is activated by the serine protease, factor IXa, in a reaction tha …
19,307 results
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